MCAS (Mast Cell Activation Syndrome) Treatment

MCAS Treatment

Mast Cell Activation Syndrome (MCAS) is a complex disorder characterized by the unpredictable and excessive release of histamine and other inflammatory mediators from mast cells. These cells are part of your immune system and play a crucial role in protecting your body from harm. However, in MCAS, mast cells become overactive, leading to a wide range of symptoms that can affect various parts of your body. At Five Journeys, we understand the challenges of living with MCAS and offer a comprehensive and holistic approach to treatment, combining conventional medicine with natural therapies to help you manage your symptoms and improve your quality of life. We believe in empowering you to take control of your health and work collaboratively with you to achieve optimal well-being.

MCAS Symptoms

MCAS can manifest in a variety of ways, sometimes causing chronic conditions that are challenging to diagnose and manage. Some people experience mild and infrequent symptoms, while others have severe and persistent symptoms that significantly impact their daily lives.

Skin Symptoms

  • Flushing: Sudden redness or warmth in your face, neck, or chest can be a common symptom of MCAS.
  • Hives: Itchy, raised welts on your skin can appear and disappear suddenly.
  • Angioedema: Swelling beneath the surface of your skin, often affecting the lips, eyes, or tongue, can be a concerning symptom.

Gastrointestinal Symptoms

  • Abdominal pain: Frequent or severe abdominal pain can be debilitating.
  • Diarrhea: Loose or watery stools can disrupt daily activities.
  • Nausea: Feeling queasy or the urge to vomit can be a common symptom.
  • Bloating and gas: Excess gas and abdominal distention can be uncomfortable.

Respiratory Symptoms

  • Nasal congestion or runny nose: Persistent nasal symptoms can be bothersome.
  • Shortness of breath or wheezing: Difficulty breathing can be a concerning symptom.
  • Frequent throat clearing: A persistent urge to clear your throat can be disruptive.

Cardiovascular Symptoms

  • Low blood pressure: Feeling lightheaded or dizzy when standing up can be a symptom of MCAS.
  • Rapid or irregular heartbeat: Heart palpitations or an irregular heartbeat can be concerning.

Neurological Symptoms

  • Brain fog: Difficulty concentrating or feeling mentally sluggish can be a frustrating symptom.
  • Headaches: Frequent or severe headaches can impact your daily life.
  • Anxiety: Feeling anxious or experiencing panic attacks can be a challenging symptom.
  • Sensitivity to light or sound: Heightened sensitivity to sensory stimuli can make it difficult to tolerate certain environments.
  • Mood Disorders: MCAS can also manifest with mood disorders, such as depression and anxiety, which can significantly impact mental health and overall well-being.
  • Cognitive Dysfunction: Cognitive dysfunction, including difficulty with memory, attention, and executive function, can be a debilitating symptom of MCAS.

Interested in MCAS Treatment? Ask your provider or book a call with us!

Causes of Mast Cell Activation Syndrome

The exact causes of MCAS are still being investigated, but several factors are believed to contribute to its development. According to Valent and Akin (2019), these factors can vary from person to person, and it’s often a combination of factors that trigger mast cell activation.

Associated Disorders

Autoimmune diseases, such as rheumatoid arthritis and lupus, have been associated with an increased risk of MCAS. These conditions involve the immune system mistakenly attacking the body’s own tissues, which may contribute to mast cell activation. Similarly, chronic inflammatory disorders can also play a role in MCAS development. Genetic factors may also predispose individuals to MCAS, as a family history of the condition or related disorders can increase the likelihood of developing it.

Environmental Triggers

Exposure to common allergens, including pollen, dust mites, mold, and animal dander, can trigger mast cell activation in some individuals. These allergens can cause an immune response that leads to the release of histamine and other inflammatory mediators from mast cells. Similarly, certain chemicals found in fragrances, cleaning products, and pollution can also irritate mast cells and contribute to their activation.

Chronic Infections

Chronic infections, whether viral, bacterial, or fungal, can play a role in MCAS. Persistent infections can trigger an ongoing immune response, leading to mast cell activation and the release of inflammatory mediators.

Stress and Hormonal Factors

Stress and hormonal imbalances are also believed to influence mast cell activity. Emotional stress and hormonal fluctuations can affect the immune system, potentially contributing to mast cell activation and MCAS symptoms.

How to Prevent MCAS

Preventing MCAS can be challenging due to its complex nature and the variety of potential triggers. However, there are several steps you can take to reduce your risk of mast cell activation and manage your symptoms:

  • Identify and avoid triggers: Pay attention to your body and try to identify specific triggers that worsen your symptoms. This may involve keeping a journal to track your exposure to potential allergens, chemicals, or stressors.
  • Manage stress: Practice stress-reducing techniques such as meditation, deep breathing exercises, or yoga.
  • Maintain a healthy lifestyle: Eat a balanced diet, get regular exercise, and prioritize sleep to support your overall health and immune function.
  • Work with a healthcare professional: Seek guidance from a healthcare professional to develop a personalized prevention and management plan.
  • Rule out other conditions: It’s important to work with your doctor to rule out other conditions that may mimic MCAS, such as autoimmune diseases, endocrine disorders, or psychological conditions. This helps ensure you receive the most appropriate treatment.
  • Controlled challenges: If you suspect certain foods or medications are triggers, your doctor may recommend controlled challenges to confirm their role in your MCAS. This can help you avoid unnecessary restrictions.
MCAS Treatment

Our Comprehensive Approach to Treatment

  • Initial Assessment: Our practitioners conduct a thorough assessment to understand your unique situation, including ruling out other potential conditions and identifying your specific triggers.
  • Natural Therapies: We consider a variety of natural therapies to support detoxification and overall wellness. This may include dietary modifications, such as increasing your intake of specific nutrients and antioxidants and incorporating herbal remedies and other supportive practices.
  • Personalized Plan: We work collaboratively with you to develop a personalized treatment plan that addresses your specific needs and goals, incorporating natural therapies and conventional approaches as necessary.

By incorporating these additional steps and considerations, you can enhance the comprehensiveness and value of your content, providing readers with a more informed and holistic approach to preventing and managing MCAS.

Why Choose Five Journeys?

At Five Journeys, we offer a comprehensive and holistic approach to MCAS treatment, focusing on natural therapies to support your body’s detoxification processes and restore overall well-being. Our experienced practitioners understand the profound impact MCAS can have on your health and are dedicated to providing personalized care that empowers you to regain control. We recognize that each individual is unique, and we tailor our treatment plans to address your specific needs and health goals.

Holistic Approach

At Five Journeys, we recognize that true wellness encompasses more than just physical health. We take a holistic approach that considers all aspects of your well-being, including physical, emotional, mental, and spiritual health.

Personalized Care

We understand that each individual is unique, and their health needs are different. That's why we tailor our services to meet your specific needs and goals. Whether you're seeking preventive care, managing chronic conditions, or optimizing your overall health, we provide personalized solutions that prioritize your well-being.

If you’re seeking effective MCAS treatment or a cure for mast cell activation syndrome, Five Journeys offers a unique and supportive approach. We understand the challenges of living with MCAS and are dedicated to providing compassionate, individualized care that helps you manage your symptoms and improve your quality of life. Our holistic approach combines conventional medicine with natural therapies to address the root causes of your condition and support your overall well-being. Don’t let MCAS control your life any longer. Schedule a consultation in Boston and Newton today and discover how we can help you reclaim your vitality and live your best life.

*Massachusetts law does not allow us to accept MassHealth & Medicaid. Other exceptions may apply.

References

  1. Castells, M., & Butterfield, J. H. (2019). Mast cell activation syndrome and mastocytosis: Initial treatment options and long-term management. The Journal of Allergy and Clinical Immunology: In Practice, 7(4), 1097-1106. https://doi.org/10.1016/j.jaip.2019.02.002
  2. Valent, P., & Akin, C. (2019). Doctor, I think I am suffering from MCAS: Differential diagnosis and separating facts from fiction. The Journal of Allergy and Clinical Immunology: In Practice, 7(4), 1109-1114. https://doi.org/10.1016/j.jaip.2018.11.045
  3. Weinstock, L. B., Nelson, R. M., & Blitshteyn, S. (2023). Neuropsychiatric Manifestations of Mast Cell Activation Syndrome and Response to Mast-Cell-Directed Treatment: A Case Series. Journal of Personalized Medicine, 13(11), 1562. https://doi.org/10.3390/jpm13111562

Why we do, What we do...

WHY DO WE DO THIS TEST?

This test is comprehensive testing for Lyme disease and other tick-borne illnesses, helping clinicians accurately diagnose and treat these complex infections. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Blood, Urine, or Ticks

COST

may have a $200 copay

INSURANCE

Covered by most insurance.

WHY DO WE DO THIS TEST?

Galleri® is a multi-cancer early detection test, a blood test that screens for many of the deadliest cancers before they become symptomatic,1,2,3 including those with no recommended screening tests today. Click here for more information.

LOCATION PERFORMED

At home or in lab.

SPECIMEN TYPE

Blood

COST

$999

INSURANCE

Depending on insurance coverage.

3 x 4 Genetics DNA Test

WHY DO WE DO THIS TEST?

This DNA test analyzes a person’s genetic markers to provide insights into their health and wellness price. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Swab

COST

$299

INSURANCE

Depending on insurance coverage.

WHY DO WE DO THIS TEST?

This test is a key tool for assessing the impact of long-term exposure to environmental chemicals. By quantitatively measuring 14 select metabolites, this test helps determine an individual’s toxic burden, offering essential data to guide targeted nutritional and detoxification interventions for improved health outcomes. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Urine

COST

$129

INSURANCE

Depending on insurance coverage.

WHY DO WE DO THIS TEST?

The Hormone and Urinary Metabolites Assessment Profile (HuMapTM) provides a comprehensive overview of steroid hormones, their metabolites, and the efficiency of the enzymes that metabolize these hormones. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Urine

COST

$199

INSURANCE

Depending on insurance coverage.

INSTRUCTIONS

WHY DO WE DO THIS TEST?

This is a dried urine test for comprehensive hormones to help providers solve complex patient cases. DUTCH is a group of validated tests that provide a complete evaluation of sex and adrenal hormones, including metabolites. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Urine

COST

$300

INSURANCE

Depending on insurance coverage.

INSTRUCTIONS

WHY DO WE DO THIS TEST?

This is a comprehensive stool test that relies on quantitative polymerase chain
reaction (qPCR) technology to detect parasites, bacteria, H. pylori, fungi, and more by targeting the specific DNA of the organisms tested. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Stool

COST

$399

INSURANCE

Depending on insurance coverage.

INSTRUCTIONS

WHY DO WE DO THIS TEST?

This is a comprehensive test that uses blood and urine to evaluate over 125 biomarkers. It provides recommendations for vitamins, minerals, amino acids, fatty acids, and digestive support. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Blood and Urine

COST

$179 – $439

INSURANCE

Depending on insurance coverage.

INSTRUCTIONS

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.
fivejourneys logo
Genova logo

WHY DO WE DO THIS TEST?

Genova’s SIBO Profiles are non-invasive breath tests which capture exhaled hydrogen (H2) and methane (CH4) gases following patient ingestion of a lactulose solution to evaluate bacterial overgrowth of the small intestine

LOCATION PERFORMED

At home

SPECIMEN TYPE

Breath

COLLECTION INSTRUCTIONS

COST

$85-$225 depending on insurance coverage. 

fivejourneys logo
RealTime

WHY DO WE DO THIS TEST?

This test evaluates the presence of harmful mycotoxins (toxins produced by molds).

LOCATION PERFORMED

At Home

SPECIMEN TYPE

Urine

COLLECTION INSTRUCTIONS

SPECIAL INSTRUCTIONS

Glutathione for 1 week, then bath or sauna.

COST

$699

INSURANCE

Fully covered by Medicare. Repeat test prices $249

fivejourneys logo
Nordic-Labratories

WHY DO WE DO THIS TEST?

This test evaluates the genetic profile for multiple health indicators. Click here for more information.

LOCATION PERFORMED

At home

SPECIMEN TYPE

Blood Spot

COST

$319

INSURANCE

No insurance accepted

COLLECTION INSTRUCTIONS

fivejourneys logo
IGX

WHY DO WE DO THIS TEST?

This company can test for lyme, babesia, bartonella and additional tick-borne illnesses. Click here for more information.

LOCATION PERFORMED

In office

SPECIMEN TYPE

Blood

COST

around $1600 (depends on panel selected)

INSURANCE

Fully covered by Medicare. May be reimbursed with PPO plans.
fivejourneys logo
Great-Plains

WHY DO WE DO THIS TEST?

This test evaluates the presence of harmful mycotoxins (toxins produced by molds).

LOCATION PERFORMED

At home

BLOOD FLUID

Urine

SPECIAL INSTRUCTIONS

Glutathione for 1 week, then bath or sauna.

COST

$310

INSURANCE

No insurance accepted
fivejourneys logo
Alletess

WHY DO WE DO THIS TEST?

This test evaluates a wide range of environmental toxins that may be leading to harmful health effects.

LOCATION PERFORMED

At home

BLOOD FLUID

Urine

SPECIAL INSTRUCTIONS

Glutathione for 1 week, then bath or sauna.

COST

$199

INSURANCE

No insurance accepted $30 discount given if done with mycotoxins.
fivejourneys logo
Quest

WHY DO WE DO THIS TEST?

Blood work for blood count, urinalysis and vitamin levels.

LOCATION PERFORMED

BLOOD FLUID

Blood

NOTES

You often have to fast for these tests-please check your providers notes.

COST

Depending on the test, deductible or copay may apply.

INSURANCE

Depends on insurance coverage, deductible or copay may apply.
fivejourneys logo
Great-Plains

WHY DO WE DO THIS TEST?

Glyphosate (“Round Up”) is a pesticide that is widely used and this test indicates the body’s levels.

LOCATION PERFORMED

At home

BLOOD FLUID

Urine

SPECIAL INSTRUCTIONS

Glutathione for 1 week, then bath or sauna.

COST

$99 ($69 if performed with mycotoxins or environmental toxins).

INSURANCE

No insurance accepted $30 discount given if done with mycotoxins or GPL Tox.
fivejourneys logo
Genova logo

WHY DO WE DO THIS TEST?

This test evaluates many measures including micronutrients, antioxidants, minerals, detox, overview of gut function, omegas and toxic exposure. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Urine

COST

$150 – $329

INSURANCE

Depending on insurance coverage. Fully covered by Medicare.

INSTRUCTIONS

fivejourneys logo
Genova logo

WHY DO WE DO THIS TEST?

This test evaluates the gut function and indicates microbiome balance, overgrowth, infection, inflammation, parasites and digestive efficacy. Click here for more information.

LOCATION PERFORMED

At home

SPECIMEN TYPE

Stool

COST

$179-$439 depending on insurance coverage.

INSURANCE

Depending on insurance coverage. Fully covered by Medicare.

SPECIAL INSTRUCTIONS

No probiotics for one week.

VIDEO INSTRUCTIONS

fivejourneys logo
Genova logo

WHY DO WE DO THIS TEST?

This test evaluates the full menstrual cycle, female hormones, and adrenal profile.

LOCATION PERFORMED

At home

BLOOD FLUID

Urine

COST

$160-$329

INSURANCE

Depending on insurance coverage. Fully covered by Medicare.

NOTES

Must be off hormones in order to do the testing.
fivejourneys logo
Galaxy

WHY DO WE DO THIS TEST?

This test is specifically for a tick-borne illness called “Bartonella”.

LOCATION PERFORMED

In office

BLOOD FLUID

Blood

COST

$260

INSURANCE

No insurance accepted
fivejourneys logo
Doctors-Data

WHY DO WE DO THIS TEST?

This test evaluates the presence of potentially harmful heavy metals stored in the body.  Click here for more information.

LOCATION PERFORMED

At home

SPECIMEN TYPE

Urine

COST

Testing: $79 x2 paid to Doctor’s Data
DMSA: $38 paid to Johnson’s Compounding Pharmacy

INSURANCE

Not covered by Insurance
fivejourneys logo
DiagnosTechs

WHY DO WE DO THIS TEST?

This test measures saliva cortisol testing throughout the course of one day and informs us where there might be an adrenal imbalance.

LOCATION PERFORMED

At home

BLOOD FLUID

Saliva

COST

$80

INSURANCE

No insurance coverage

fivejourneys logo
Alletess

WHY DO WE DO THIS TEST?

This test is designed to look at food sensitivities (IgG immune responses). It is available in both a 99 or 184 panel. Click here for more information.

LOCATION PERFORMED

In office

SPECIMEN TYPE

Blood

COST

$129-238

INSURANCE

No insurance accepted