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Insulin Resistance: Understanding the Causes and Solutions

Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

Imagine your body’s cells have tiny doors that allow sugar (glucose) to enter and provide energy. Insulin, a hormone made by your pancreas, acts like a key that unlocks these doors.

In insulin resistance, these doors become “rusty” and don’t open easily, even with plenty of insulin keys around. This means sugar can’t get into your cells effectively, leading to a buildup in your bloodstream. This buildup can cause a range of health problems, from weight gain and fatigue to more serious conditions like type 2 diabetes, polycystic ovary syndrome (PCOS), and even heart disease. But don’t worry! Understanding insulin resistance is the first step towards taking control of your health. This blog post will break down the complexities of insulin resistance in a clear, easy-to-understand way, empowering you to make informed choices for your health.

 

What Causes Insulin Resistance?

Several factors contribute to insulin resistance, and they often work in combination:

Lifestyle Factors

Poor Diet

A diet high in processed foods, sugary drinks, and unhealthy fats overloads your body with glucose, forcing your pancreas to pump out more and more insulin. Eventually, your cells become desensitized to this constant barrage of insulin, leading to resistance.

Lack of Exercise

Regular physical activity helps muscles use glucose for energy, improving insulin sensitivity. A sedentary lifestyle, on the other hand, increases your risk of insulin resistance.

Chronic Stress

When stressed, your body releases cortisol, a hormone that can interfere with insulin signaling.

Sleep Deprivation

Poor sleep disrupts your body’s natural hormonal balance, including insulin production and sensitivity.

Hormonal Imbalances

Adiponectin

Adinopectin, a hormone produced by fat cells, is crucial in improving insulin sensitivity. Low levels of adiponectin are often linked to insulin resistance. 

Other Hormones

Imbalances in cortisol, thyroid hormones, and other hormones can also contribute to insulin resistance.

Genetic Predisposition

While lifestyle plays a major role, genetics can also make some individuals more susceptible to insulin resistance.

 

Signs of Insulin Resistance

  • Increased thirst and frequent urination
  • Difficulty concentrating (“brain fog”)
  • Skin tags or dark patches on the skin (Acanthosis nigricans)
  • Intense sugar cravings When your cells aren’t utilizing glucose efficiently, your body craves quick sources of energy, leading to strong desires for sugary foods and drinks

 

Reversing Insulin Resistance with a Holistic Approach

Taking a holistic approach to your health is key to addressing the root causes of insulin resistance and regaining control of your well-being. This involves making sustainable lifestyle changes and seeking guidance from qualified healthcare professionals.

Comprehensive Testing

Work with your doctor or a functional medicine practitioner to assess your insulin sensitivity, identify hormonal imbalances, and uncover any underlying nutritional deficiencies.

Personalized Nutrition

A registered dietitian can help you create a customized nutrition plan that prioritizes whole foods, healthy fats, and blood sugar balance. This will help stabilize your blood sugar levels and improve your body’s response to insulin.

Lifestyle Modifications

Focus on incorporating healthy habits into your routine, including regular exercise, stress management techniques (like meditation or yoga), and getting enough quality sleep. These lifestyle changes are crucial for improving insulin sensitivity and overall health.

Targeted Supplementation

In some cases, your healthcare provider may recommend supplements like berberine, magnesium, or inositol (especially beneficial for those with PCOS) to further support your insulin sensitivity.

Intermittent Fasting

Consider exploring intermittent fasting under the guidance of a healthcare professional. It can be an effective tool for improving insulin sensitivity and promoting weight loss.

 

Benefits of Reversing Insulin Resistance

By addressing insulin resistance, you can experience a wide range of benefits, including:

  • Increased energy levels
  • Healthy weight management
  • Reduced risk of chronic diseases like type 2 diabetes and heart disease
  • Improved mood and cognitive function

 

Take the First Step with Five Journeys

Ready to break free from the grip of insulin resistance and reclaim your health? Schedule a free consultation with Five Journeys today. Our team of expert functional medicine practitioners in Boston and Newton is dedicated to helping you achieve optimal well-being. 

To learn more about how functional medicine can help address insulin resistance, check out this article:

Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test is comprehensive testing for Lyme disease and other tick-borne illnesses, helping clinicians accurately diagnose and treat these complex infections. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Blood, Urine, or Ticks

COST

may have a $200 copay

INSURANCE

Covered by most insurance.

Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

Galleri® is a multi-cancer early detection test, a blood test that screens for many of the deadliest cancers before they become symptomatic,1,2,3 including those with no recommended screening tests today. Click here for more information.

LOCATION PERFORMED

At home or in lab.

SPECIMEN TYPE

Blood

COST

$999

INSURANCE

Depending on insurance coverage.

Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This DNA test analyzes a person’s genetic markers to provide insights into their health and wellness price. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Swab

COST

$299

INSURANCE

Depending on insurance coverage.

Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test is a key tool for assessing the impact of long-term exposure to environmental chemicals. By quantitatively measuring 14 select metabolites, this test helps determine an individual’s toxic burden, offering essential data to guide targeted nutritional and detoxification interventions for improved health outcomes. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Urine

COST

$129

INSURANCE

Depending on insurance coverage.

Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

The Hormone and Urinary Metabolites Assessment Profile (HuMapTM) provides a comprehensive overview of steroid hormones, their metabolites, and the efficiency of the enzymes that metabolize these hormones. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Urine

COST

$199

INSURANCE

Depending on insurance coverage.

INSTRUCTIONS

Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This is a dried urine test for comprehensive hormones to help providers solve complex patient cases. DUTCH is a group of validated tests that provide a complete evaluation of sex and adrenal hormones, including metabolites. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Urine

COST

$300

INSURANCE

Depending on insurance coverage.

INSTRUCTIONS

Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This is a comprehensive stool test that relies on quantitative polymerase chain
reaction (qPCR) technology to detect parasites, bacteria, H. pylori, fungi, and more by targeting the specific DNA of the organisms tested. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Stool

COST

$399

INSURANCE

Depending on insurance coverage.

INSTRUCTIONS

Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This is a comprehensive test that uses blood and urine to evaluate over 125 biomarkers. It provides recommendations for vitamins, minerals, amino acids, fatty acids, and digestive support. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Blood and Urine

COST

$179 – $439

INSURANCE

Depending on insurance coverage.

INSTRUCTIONS

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Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

Genova’s SIBO Profiles are non-invasive breath tests which capture exhaled hydrogen (H2) and methane (CH4) gases following patient ingestion of a lactulose solution to evaluate bacterial overgrowth of the small intestine

LOCATION PERFORMED

At home

SPECIMEN TYPE

Breath

COLLECTION INSTRUCTIONS

COST

$85-$225 depending on insurance coverage. 

Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test evaluates the presence of harmful mycotoxins (toxins produced by molds).

LOCATION PERFORMED

At Home

SPECIMEN TYPE

Urine

COLLECTION INSTRUCTIONS

SPECIAL INSTRUCTIONS

Glutathione for 1 week, then bath or sauna.

COST

$699

INSURANCE

Fully covered by Medicare. Repeat test prices $249

Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test evaluates the genetic profile for multiple health indicators. Click here for more information.

LOCATION PERFORMED

At home

SPECIMEN TYPE

Blood Spot

COST

$319

INSURANCE

No insurance accepted

COLLECTION INSTRUCTIONS

Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This company can test for lyme, babesia, bartonella and additional tick-borne illnesses. Click here for more information.

LOCATION PERFORMED

In office

SPECIMEN TYPE

Blood

COST

around $1600 (depends on panel selected)

INSURANCE

Fully covered by Medicare. May be reimbursed with PPO plans.
Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test evaluates the presence of harmful mycotoxins (toxins produced by molds).

LOCATION PERFORMED

At home

BLOOD FLUID

Urine

SPECIAL INSTRUCTIONS

Glutathione for 1 week, then bath or sauna.

COST

$310

INSURANCE

No insurance accepted
Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test evaluates a wide range of environmental toxins that may be leading to harmful health effects.

LOCATION PERFORMED

At home

BLOOD FLUID

Urine

SPECIAL INSTRUCTIONS

Glutathione for 1 week, then bath or sauna.

COST

$199

INSURANCE

No insurance accepted $30 discount given if done with mycotoxins.
Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

Blood work for blood count, urinalysis and vitamin levels.

LOCATION PERFORMED

BLOOD FLUID

Blood

NOTES

You often have to fast for these tests-please check your providers notes.

COST

Depending on the test, deductible or copay may apply.

INSURANCE

Depends on insurance coverage, deductible or copay may apply.
Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

Glyphosate (“Round Up”) is a pesticide that is widely used and this test indicates the body’s levels.

LOCATION PERFORMED

At home

BLOOD FLUID

Urine

SPECIAL INSTRUCTIONS

Glutathione for 1 week, then bath or sauna.

COST

$99 ($69 if performed with mycotoxins or environmental toxins).

INSURANCE

No insurance accepted $30 discount given if done with mycotoxins or GPL Tox.
Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test evaluates many measures including micronutrients, antioxidants, minerals, detox, overview of gut function, omegas and toxic exposure. Click here for more information.

LOCATION PERFORMED

At home.

SPECIMEN TYPE

Urine

COST

$150 – $329

INSURANCE

Depending on insurance coverage. Fully covered by Medicare.

INSTRUCTIONS

Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test evaluates the gut function and indicates microbiome balance, overgrowth, infection, inflammation, parasites and digestive efficacy. Click here for more information.

LOCATION PERFORMED

At home

SPECIMEN TYPE

Stool

COST

$179-$439 depending on insurance coverage.

INSURANCE

Depending on insurance coverage. Fully covered by Medicare.

SPECIAL INSTRUCTIONS

No probiotics for one week.

VIDEO INSTRUCTIONS

Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test evaluates the full menstrual cycle, female hormones, and adrenal profile.

LOCATION PERFORMED

At home

BLOOD FLUID

Urine

COST

$160-$329

INSURANCE

Depending on insurance coverage. Fully covered by Medicare.

NOTES

Must be off hormones in order to do the testing.
Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test is specifically for a tick-borne illness called “Bartonella”.

LOCATION PERFORMED

In office

BLOOD FLUID

Blood

COST

$260

INSURANCE

No insurance accepted
Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test evaluates the presence of potentially harmful heavy metals stored in the body.  Click here for more information.

LOCATION PERFORMED

At home

SPECIMEN TYPE

Urine

COST

Testing: $79 x2 paid to Doctor’s Data
DMSA: $38 paid to Johnson’s Compounding Pharmacy

INSURANCE

Not covered by Insurance
Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test measures saliva cortisol testing throughout the course of one day and informs us where there might be an adrenal imbalance.

LOCATION PERFORMED

At home

BLOOD FLUID

Saliva

COST

$80

INSURANCE

No insurance coverage

Insulin Resistance: Understanding the Causes and Solutions
Insulin Resistance: Understanding the Causes and Solutions

WHY DO WE DO THIS TEST?

This test is designed to look at food sensitivities (IgG immune responses). It is available in both a 99 or 184 panel. Click here for more information.

LOCATION PERFORMED

In office

SPECIMEN TYPE

Blood

COST

$129-238

INSURANCE

No insurance accepted