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About the Episode

Improve your lifestyle and prevent Alzheimer’s!

Join board-certified neurologist, Dr. David Perlmutter, as he dives deep into the importance of making dietary and lifestyle choices that support brain health and reduce the risk of Alzheimer’s.

Listen now and learn to start taking better care of your brain today!

What We Discuss

The factors associated with Alzheimer’s disease present a multidimensional view of its causation. We must broaden our understanding of Alzheimer’s and find new avenues for research and potential strategies for prevention and treatment.

Since Alzheimer’s disease is influenced by multiple interconnected, making healthier lifestyle choices might be one of the best ways to prevent this disease.

Risk Factors for Alzheimer’s

While beta-amyloid has been a prominent focus in Alzheimer’s research, clinging to a single theory, such as the “amyloid hypothesis,” has proven inadequate in finding effective treatments for the disease. In order to get a deeper understanding, we must look at the multiple, interconnected components that contribute to it.

One significant factor in Alzheimer’s risk is gender, with two-thirds of patients being women. This discrepancy prompts an exploration into hormonal influences and genetic factors that may contribute to the increased susceptibility of women to the disease.

Type 2 diabetes, often linked to lifestyle choices, also significantly raises the likelihood of developing Alzheimer’s. Higher risk begins at an A1C as low as 5.3-5.4, challenging the conventional belief that only high blood sugar levels warrant attention. Lowering A1C levels through pharmaceutical interventions may not address impaired glucose utilization in brain cells due to insulin resistance, one root causes of Alzheimer’s.

Insulin resistance in brain cells impairs their ability to utilize glucose effectively, leading to energy deficits and ultimately cell death. This bioenergetic theory implicates insulin functionality as not only a regulator of glucose entry into cells but also as a trophic hormone that nurtures brain cells.

Exercise for Reducing Alzheimer’s Risk

Exercise is not only a means of keeping the body in shape but also one of the most important things you can do for your brain’s health. Research studies have shown that individuals who engage in regular physical activity, whether through walking, jogging, biking, or other forms of exercise, experience a significant reduction in their risk of developing Alzheimer’s.

One key mechanism is the production of Brain-Derived Neurotrophic Factor (BDNF). Exercise is known to boost the body’s production of BDNF, which is essential for promoting the growth of new brain cells, enhancing the connections between each other, protecting them against damage, and supporting overall brain function.

Individuals with type 2 diabetes, a preventable lifestyle-related condition often linked to obesity and poor dietary choices, face a dramatically increased risk of Alzheimer’s. However, exercise is shown to be effective in improving insulin function, not only in the body but also in the brain. One study even demonstrates that regular exercise can restore insulin sensitivity in the brain, thereby reducing the risk of cognitive decline.

Diet and Alzheimer’s

A ketogenic diet, which is low in carbohydrates and high in healthy fats, can enhance brain function and has been shown to improve cognitive function in Alzheimer’s patients. It promotes the production of ketones, an alternative energy source for brain cells, which can be particularly helpful for individuals with insulin resistance.

Elevated blood sugar levels, often due to poor dietary choices, can increase the risk of Alzheimer’s. Highly processed and sugary foods are also linked to inflammation, which is a known contributor to Alzheimer’s disease. A diet rich in fiber and plant-based foods can support a healthy gut microbiome, which in turn influences brain health. Avoiding processed and unhealthy foods and maintaining stable blood sugars is key to reducing your risk of cognitive decline.

Toxins And Detoxification

Our modern world is teeming with environmental toxins, many of which have emerged only recently. These toxins are a concern because our bodies haven’t had enough time to adapt and effectively detoxify these newcomers.Toxins have a major impact on our overall health, and they may even contribute to Alzheimer’s disease.

2.5-micron particles are minuscule bits of matter associated with various chronic health issues, including cognitive decline. Living close to highways and exposure to these particles have been linked to a higher risk of developing Alzheimer’s. Toxins, like air pollutants and mold, can contribute to chronic inflammation within our bodies. This inflammation is recognized as a key player in Alzheimer’s disease and other chronic conditions, exacerbating the connection between toxins and cognitive health.

Maintaining a healthy lifestyle and making wise dietary choices can bolster our body’s natural detoxification mechanisms, aiding in the elimination of toxins from the body.

Listen now to lower your risk of Alzheimer’s disease today!

Guest Bio

David Perlmutter, MD, is a board-certified neurologist and Fellow of the American College of Nutrition. He is a frequent lecturer at symposia sponsored by institutions including the World Bank, Columbia University, New York University, Yale, and Harvard, and serves as an Associate Professor at the University of Miami Miller School of Medicine.

He is a five-time New York Times bestselling author and the recipient of numerous awards, including: the Linus Pauling Award for his innovative approaches to neurological disorders; the National Nutritional Foods Association Clinician of the Year Award; and the Humanitarian of the Year award from the American College of Nutrition.

He maintains an active blog at DrPerlmutter.com and is the author of Brain Wash, Grain Brain, Brain Maker, The Grain Brain Whole Life Plan, The Grain Brain Cookbook, and Raise a Smarter Child by Kindergarten. Dr. Perlmutter has been interviewed on many nationally syndicated television programs Including 20/20, CNN, Fox News, Fox and Friends, The Today Show, Oprah, The Dr. Oz Show, The CBS Early Show, and CBS This Morning

Links

https://www.facebook.com/DavidPerlmutterMd
https://twitter.com/davidperlmutter
https://www.youtube.com/user/DavidPerlmutterMD
https://www.instagram.com/davidperlmutter/
https://www.drperlmutter.com/
https://www.drperlmutter.com/learn/empowering-neurologist/
https://www.drperlmutter.com/learn/books/

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