Introducing a powerful, cutting-edge supplement designed to support and enhance healthy NAD+ levels—vital for energy, cellular repair, and overall vitality. This innovative formula combines NMN (Nicotinamide Mononucleotide), a precursor to NAD+, with TMG(Trimethylglycine), which helps optimize methylation and support detoxification. Added Pterostilbene, a potent antioxidant, helps protect cells from oxidative stress while promoting healthy aging, and Apigenin, a natural flavonoid, further supports cellular health and cognitive function. Together, these ingredients work synergistically to elevate NAD+ levels, boost energy support, improve metabolic function, and promote longevity.
Nicotinamide Mononucleotide (NMN): 1,000mg
Key Benefits:
- Boosts NAD+ Levels: NMN is a direct precursor to NAD+, an essential molecule for energy production and cellular repair. By replenishing NAD+, NMN combats age-related declines in mitochondrial function and supports optimal metabolism.
- Supports Longevity Pathways: NMN activates sirtuins, enzymes that regulate DNA repair, inflammation control, and cellular health.
- Enhances Physical and Cognitive Performance: Higher NAD+ levels improve endurance, recovery, and brain function.
Scientific Evidence:
- Studies show NMN supplementation restores NAD+ levels, improving mitochondrial function and lifespan in animal models【1】
- Human trials demonstrate NMN’s ability to enhance blood flow and muscle oxygenation【2】
Trimethylglycine (TMG) (as Betaine Anhydrous): 500mg
Key Benefits:
- Supports Methylation Processes: TMG acts as a methyl donor, critical for processing homocysteine into methionine. This helps maintain healthy DNA and supports NMN’s conversion into NAD+.
- Protects Cells from Stress: TMG stabilizes proteins and cell membranes under osmotic stress, ensuring cellular integrity.
- Supports Heart and Liver Health: Helps support homocysteine levels and cardiovascular risk factors.
Scientific Evidence:
- Research highlights TMG’s role in enhancing cellular methylation and metabolic efficiency【3】【4】
- TMG improves physical endurance and energy production in athletes【5】
Pterostilbene: 50mg
Key Benefits:
- Antioxidant Powerhouse: A more bioavailable analog of resveratrol, pterostilbene neutralizes free radicals and protects against oxidative damage.
- Activates Sirtuins: Supports longevity by enhancing sirtuin activity, which depends on NAD+.
- Supports Cognitive Function: Protects brain cells from age-related decline, enhancing memory and focus.
Scientific Evidence:
- Studies suggest pterostilbene is more bioavailable and effective than resveratrol at promoting cellular health【6】【7】.
- Pterostilbene has anti-inflammatory effects, supporting cardiovascular and brain health【8】.
Apigenin: 50mg
Key Benefits:
- Inhibits CD38: Apigenin blocks CD38, an enzyme that depletes NAD+ levels, ensuring more NAD+ is available for critical cellular processes.
- Anti-Inflammatory Properties: Supports chronic inflammation, a key driver of aging and age-related diseases.
- Protects Against Oxidative Stress: Enhances cellular resilience by reducing oxidative damage to DNA, proteins, and lipids.
Scientific Evidence:
- Research confirms apigenin’s ability to inhibit CD38 and increase NAD+ availability【9】【10】.
- Apigenin also shows neuroprotective effects, supporting healthy brain aging【11
The Synergy of Science
By combining these four powerhouse ingredients, NMN 1000+ supports NAD+ production through multiple pathways:
- NMN: Directly replenishes NAD+ levels.
- TMG: Facilitates NMN metabolism via methylation.
- Pterostilbene: Protects and enhances NAD+ and Sirtuin activity.
- Apigenin: Reduces NAD+ depletion by inhibiting CD38.
